Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619569 | 0.74 | ESR1 (0.40) | MEN1CYP3A4KMT2AHPGD | |
| SCHEMBL20380857 | 0.70 | EGFR (0.35) | MEN1CYP3A4KMT2APTGS1DRD3 | |
| SCHEMBL28805870 | 0.69 | CYP3A4 (0.41) | MEN1CYP3A4KMT2APTGS1DRD3 | |
| SCHEMBL27586582 | 0.69 | ESR1 (0.39) | CYP3A4PTGS1DRD3 | |
| SCHEMBL27815420 | 0.69 | CA1 (0.46) | — | |
| SCHEMBL27916550 | 0.68 | ERN1 (0.34) | — | |
| SCHEMBL6439294 | 0.63 | MAPT (0.36) | MEN1CYP3A4KMT2APTGS1DRD3 | |
| SCHEMBL7079260 | 0.62 | HSD17B10 (0.35) | MEN1CYP3A4KMT2AHPGD | |
| SCHEMBL15653587 | 0.61 | HIF1A (0.33) | MEN1CYP3A4KMT2AHPGD | |
| SCHEMBL10404684 | 0.60 | TYR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103360352-B | Total synthesis method for 4-methoxy-2,6-dihydroxy-2-benzyl-3(2H)-benzofuranone | INST MEDICINAL PLANT DEV CAMS | 2015-07-08 | — | — | CN | disclosed |
| CN-103360352-A | Total synthesis method for 4-methoxy-2,6-dihydroxy-2-benzyl-3(2H)-benzofuranone | INST MEDICINAL PLANT DEV CAMS | 2013-10-23 | — | — | CN | disclosed |