Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274961 | 0.82 | HTT (0.44) | TYRHSP90AB1 | |
| SCHEMBL8590396 | 0.79 | ESR1 (0.41) | — | |
| SCHEMBL9500981 | 0.78 | TSHR (0.57) | TYRCA12CA2CA14 | |
| SCHEMBL27536513 | 0.76 | TYR (0.50) | TYRCA12CA1CA2CA7 | |
| SCHEMBL5439730 | 0.75 | TYR (0.53) | TYRHSP90AB1 | |
| SCHEMBL21830477 | 0.75 | TYR (0.48) | TYRHSP90AB1 | |
| SCHEMBL29492305 | 0.75 | TYR (0.48) | TYRHSP90AB1 | |
| SCHEMBL31544892 | 0.75 | LMNA (0.50) | TYRHSP90AB1 | |
| SCHEMBL27886552 | 0.74 | NPC1 (0.46) | — | |
| SCHEMBL10404681 | 0.74 | HSP90AB1 (0.47) | TYRHSP90AB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963463-A | Radiation-sensitive resin composition with admixtures of O-quinone diazide and acid esters having nitrobenzyl or cyanobenzyl group | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0330406-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |