Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.71 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | QPCT | Q16769 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27941633 | 0.95 | MTNR1A (0.64) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL358772 | 0.86 | MTNR1A (0.74) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL3396218 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL30080294 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL28807981 | 0.82 | SMN1; SMN2 (0.66) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13753680 | 0.81 | POLB (0.70) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3822948 | 0.81 | MAPT (0.81) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL30557433 | 0.81 | MAPT (0.81) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL27941616 | 0.81 | KMT2A (0.56) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL10077284 | 0.79 | KMT2A (0.67) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373969-A | Phenyl imidazole ring-substituted amide compounds as well as preparation method and application for same | SHANGHAI INST ORGANIC CHEM | 2013-10-30 | — | — | CN | disclosed |