Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918061 | 0.90 | EGLN1 (0.54) | HPGDKMT2AKDM1AHDAC1EGLN1 | |
| SCHEMBL27936545 | 0.88 | POLA1 (0.57) | MAOAMAOBAKR1B1HPGDKMT2A | |
| SCHEMBL27936600 | 0.88 | APP (0.53) | MAOAMAOBHPGDKMT2AALDH1A1 | |
| SCHEMBL27918126 | 0.81 | MAOB (0.58) | MAOAMAOBAKR1B1HPGDKMT2A | |
| SCHEMBL14352883 | 0.77 | ALDH2 (0.66) | AKR1B1HPGDKMT2AALDH1A1KDM4E | |
| SCHEMBL3900807 | 0.76 | CA12 (0.60) | MAOBL3MBTL1 | |
| SCHEMBL30899849 | 0.76 | CA12 (0.55) | MAOBKDM4EL3MBTL1APP | |
| SCHEMBL3297118 | 0.75 | PPARD (0.54) | MAOBHPGDALDH1A1 | |
| SCHEMBL3210641 | 0.75 | MAOB (0.65) | MAOAMAOBHPGDALDH1A1 | |
| SCHEMBL7404629 | 0.74 | MAOB (0.60) | MAOAMAOBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | claimed |
| CN-103304438-B | N-substituted salicylamide compounds, preparation method and application | SHANDONG UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | disclosed |