Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936545 | 0.87 | POLA1 (0.57) | MAOBMAOAPOLBRAB9ANPC1 | |
| SCHEMBL27936600 | 0.87 | APP (0.53) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL27936605 | 0.83 | MAOB (0.65) | MAOBMAOARAB9ANPC1KLKB1 | |
| SCHEMBL27918061 | 0.82 | EGLN1 (0.54) | RAB9ANPC1MEN1KMT2AKLKB1 | |
| SCHEMBL27918116 | 0.82 | FADS1 (0.65) | MAOBMAOARAB9ANPC1MEN1 | |
| SCHEMBL28807425 | 0.81 | MAOA (0.55) | MAOBMAOAKMT2AKLKB1KDM4E | |
| SCHEMBL27918223 | 0.80 | CFD (0.48) | KLKB1ALDH1A1HPGDGAAHTT | |
| SCHEMBL23675443 | 0.74 | P2RX1 (0.64) | APEX1NPC1MEN1HCRTR1KMT2A | |
| SCHEMBL12998999 | 0.74 | NPC1 (0.52) | MAOBMAOAAPEX1POLBRAB9A | |
| SCHEMBL3900807 | 0.74 | CA12 (0.60) | MAOBPOLBRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | claimed |
| CN-103304438-B | N-substituted salicylamide compounds, preparation method and application | SHANDONG UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | disclosed |