Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782951 | 0.96 | FDPS (0.52) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL644279 | 0.96 | FDPS (0.52) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL288736 | 0.96 | FDPS (0.52) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL5499053 | 0.94 | KMT2A (0.51) | FDPSKMT2AMEN1LMNATP53 | |
| Hydrochloric Acid SCHEMBL645809 | 0.94 | FDPS (0.50) | FDPSKMT2AMEN1LMNATP53 | |
| Hydrochloric Acid SCHEMBL16909535 | 0.94 | FDPS (0.50) | FDPSKMT2AMEN1LMNATP53 | |
| Hydrochloric Acid SCHEMBL16909729 | 0.94 | FDPS (0.50) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL1476244 | 0.90 | — | — | |
| SCHEMBL288786 | 0.90 | — | — | |
| SCHEMBL288677 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649051-B | Process for preparing heterocyclic compounds comprising trans-7-oxo-6- (sulfooxy) -1, 6-diazabicyclo [3,2,1] octane-2-carboxamide and salts thereof | ASTRAZENECA AB (SE) | 2016-04-13 | — | — | CN | disclosed |
| CN-105294690-A | PROCESSES FOR PREPARING HETEROCYCLIC COMPOUNDS INCLUDING TRANS-7-OXO-6-(SULPHOOXY)-1,6-DIAZABICYCLO[3,2,1]OCTANE-2-CARBOXAMIDE AND SALTS THEREOF | ASTRAZENECA AB | 2016-02-03 | — | — | CN | disclosed |
| CN-103649051-A | Process for preparing heterocyclic compounds comprising trans-7-oxo-6- (sulfooxy) -1, 6-diazabicyclo [3,2,1] octane-2-carboxamide and salts thereof | ASTRAZENECA AB | 2014-03-19 | — | — | CN | disclosed |