Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192064 | 0.86 | MAPT (0.72) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28807981 | 0.85 | SMN1; SMN2 (0.66) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3781565 | 0.84 | ALDH1A1 (0.67) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2058714 | 0.84 | KMT2A (0.63) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8103859 | 0.84 | MAPT (0.70) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10192072 | 0.83 | MEN1 (0.69) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27941643 | 0.83 | EPHX1 (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9471665 | 0.83 | KMT2A (0.65) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12156588 | 0.83 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10172965 | 0.82 | NPC1 (0.68) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373969-A | Phenyl imidazole ring-substituted amide compounds as well as preparation method and application for same | SHANGHAI INST ORGANIC CHEM | 2013-10-30 | — | — | CN | disclosed |