Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494717 | 0.88 | HRH4 (0.51) | HRH4KDM4ELMNATP53L3MBTL1 | |
| SCHEMBL654862 | 0.83 | HRH4 (0.55) | HRH4ALOX15KDM4ELMNATP53 | |
| SCHEMBL17092514 | 0.83 | HRH4 (0.55) | HRH4ALOX15KDM4ELMNATP53 | |
| SCHEMBL20612119 | 0.82 | HRH4 (0.51) | HRH4ALOX15KDM4ELMNATP53 | |
| Hydrochloric Acid SCHEMBL23045607 | 0.82 | HRH4 (0.53) | HRH4ALOX15KDM4ELMNATP53 | |
| Hydrochloric Acid SCHEMBL31383573 | 0.82 | HRH4 (0.53) | HRH4ALOX15KDM4ELMNATP53 | |
| SCHEMBL6947975 | 0.81 | HRH3 (0.52) | ALOX15KDM4ELMNATP53L3MBTL1 | |
| SCHEMBL29496122 | 0.80 | KDM4E (0.63) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL318243 | 0.80 | KDM4E (0.63) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL20612118 | 0.80 | RAB9A (0.48) | ALOX15KDM4ELMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728914-B | Dioxopiperazine derivative, preparation method thereof and application thereof in medicines | 深圳信立泰药业股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114728914-A | Dioxopiperazine derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |