Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942905 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1ASLC6A2ALDH1A1KMT2A | |
| SCHEMBL30645405 | 0.81 | — | — | |
| SCHEMBL8609659 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1AKT1 | |
| SCHEMBL8609662 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1AKT1 | |
| SCHEMBL4937591 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2HIF1ASLC6A2TAAR1AKT1 | |
| SCHEMBL6464407 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2HIF1ASLC6A2TAAR1AKT1 | |
| SCHEMBL356558 | 0.79 | CHRM3 (0.36) | MGLLALDH1A1KDM4EGLAGAA | |
| SCHEMBL30287984 | 0.78 | — | — | |
| SCHEMBL27987911 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2HIF1ASLC6A2TAAR1AKT1 | |
| SCHEMBL27987912 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2HIF1ASLC6A2TAAR1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687846-A | Benzylamine derivatives as inhibitors of plasma kallikrein | KALVISTA PHARMACEUTICALS LTD | 2014-03-26 | — | — | CN | disclosed |