Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4937591 | 1.00 | SMN1; SMN2 (0.66) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL27987912 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL27987911 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL27584265 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1APPARGPPARA | |
| SCHEMBL6139605 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1APPARGPPARA | |
| SCHEMBL2844022 | 0.88 | BLM (0.59) | SMN1; SMN2HIF1ABLMRECQLCYP3A4 | |
| SCHEMBL2844025 | 0.88 | BLM (0.59) | SMN1; SMN2HIF1ABLMRECQLCYP3A4 | |
| SCHEMBL27616082 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL5844669 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ABLMPPARGPPARA | |
| SCHEMBL8609659 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121396-B | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2022-06-10 | — | — | CN | claimed |
| CN-113121396-A | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2021-07-16 | — | — | CN | claimed |
| CN-110092814-B | Amphiphilic multi-block antibacterial peptide and preparation method and application thereof | 同济大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-113121396-B | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-113121396-A | Degradable polydiseleno-containing polydopamine and preparation method and application thereof | 华南理工大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-110092814-A | Amphipathic multi-block class antibacterial peptide and its preparation method and application | 同济大学 | 2019-08-06 | — | — | CN | disclosed |
| CN-104797591-A | Fluorinated epoxyketone compounds and their use as proteasome inhibitors | SLASSI ABDELMALIK | 2015-07-22 | — | — | CN | disclosed |
| CN-104523702-A | Application of phenylalanine cyclopentanoperhydro-phenanthrene ester in preparation of hypotensor | UNIV JILIN AGRICULTURAL | 2015-04-22 | — | — | CN | disclosed |
| CN-102753538-B | Sultam derivatives | HOFFMANN LA ROCHE | 2015-04-08 | — | — | CN | disclosed |
| CN-1914224-B | HCV NS-3 serine protease inhibitors | MEDIVIR AB | 2014-01-29 | — | — | CN | disclosed |
| CN-103097373-A | Pro-drugs of (e) -7- (3- (2-amino-1-fluoroethylidene) piperidin-1-yl) -1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JANSSEN PHARMACEUTICA NV | 2013-05-08 | — | — | CN | disclosed |
| CN-1678372-A | Heterocyclic aromatic compounds useful as growth hormone secretagogues | BRISTOL MYERS SQUIBB CO (US) | 2005-10-05 | — | — | CN | disclosed |
| EP-1526134-A2 | TRIAZOLYL TROPANE DERIVATIVES AS CCR5 MODULATORS | Pfizer Limited (GB) | 2005-04-27 | — | — | EP | disclosed |
| EP-1013276-A1 | Aminoazacycloalkanes as CCR5 modulators | PFIZER INC. (US) | 2000-06-28 | — | — | EP | disclosed |
| US-5830869-A | METALLOPROTEASE INHIBITOR | PHARMACIA & UPJOHN COMPANY | 1998-11-03 | — | — | US | disclosed |
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4880781-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |
| EP-0036713-A2 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-30 | — | — | EP | disclosed |