Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806708 | 0.86 | MEN1 (0.55) | MEN1KMT2A | |
| SCHEMBL12466880 | 0.85 | MEN1 (0.64) | GAAMEN1KMT2AFAAH | |
| SCHEMBL22265834 | 0.79 | CYP2C9 (0.48) | — | |
| SCHEMBL3145386 | 0.79 | KDM4E (0.52) | — | |
| SCHEMBL12685846 | 0.77 | MEN1 (0.85) | MEN1KMT2AFAAH | |
| SCHEMBL22265922 | 0.76 | CCR3 (0.50) | MEN1KMT2A | |
| SCHEMBL21763292 | 0.76 | TACR3 (0.71) | GAAMEN1KMT2AFAAH | |
| Hydrochloric Acid SCHEMBL12466326 | 0.76 | MEN1 (0.83) | MEN1KMT2AFAAH | |
| SCHEMBL12466499 | 0.76 | KMT2A (0.67) | MEN1KMT2AFAAH | |
| SCHEMBL12466321 | 0.76 | MEN1 (0.67) | MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103339108-A | Protease activated receptor 2 (par2) antagonists | PROXIMAGEN LTD | 2013-10-02 | — | — | CN | claimed |
| CN-103339108-A | Protease activated receptor 2 (par2) antagonists | PROXIMAGEN LTD | 2013-10-02 | — | — | CN | disclosed |