Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.62 |
| ▸ | TACR3 | P29371 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21763292 | 0.90 | TACR3 (0.71) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL2636547 | 0.86 | MEN1 (0.68) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL28808573 | 0.85 | GAA (0.48) | MEN1KMT2AFAAHGAA | |
| SCHEMBL3026559 | 0.85 | CYP2C9 (0.67) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL4576736 | 0.85 | L3MBTL1 (0.69) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL27924584 | 0.84 | ALDH1A1 (0.54) | FAAHCYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL5806708 | 0.84 | MEN1 (0.55) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL7362106 | 0.84 | ALDH1A1 (0.64) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL7419173 | 0.83 | CYP2C9 (0.65) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL8337998 | 0.83 | MGLL (0.62) | MEN1KMT2AFAAHMGLLTACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139471-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-13 | — | — | US | disclosed |
| CN-109761883-A | A kind of 4- carbamate-cinnamamide -4- benzyl piperidine coumpound and its preparation method and application | 南阳师范学院 | 2019-05-17 | — | — | CN | disclosed |
| CN-109678795-A | 4- carbamate-asafoetide amide -1,2,3,4- tetrahydroisoquinolicompounds compounds and its preparation method and application | 南阳师范学院 | 2019-04-26 | — | — | CN | disclosed |
| US-20130324556-A1 | Protease Activated Receptor 2 (PAR2) Antagonists | PROXIMAGEN LTD. (GB) | 2013-12-05 | — | — | US | disclosed |
| EP-2668157-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | Proximagen Limited (GB) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012101453-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | PROXIMAGEN LTD. (GB) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130324556-A1 | Protease Activated Receptor 2 (PAR2) Antagonists | F2RL1, F2R, F2RL3 | MEN1 1376/4885KMT2A 2337/4885FAAH 725/4885 |
| US-20210139471-A1 | COMPOUNDS AND USES THEREOF | NLN, BDNF, NQO1 | MEN1 191/4885KMT2A 587/4885FAAH 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.