Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806007 | 0.81 | UHRF1 (0.43) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL29187018 | 0.81 | KDM4E (0.37) | KDM4ESMN1; SMN2ALDH1A1LOXL2MAPT | |
| SCHEMBL3831255 | 0.80 | KIF11 (0.38) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL129055 | 0.79 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL29608524 | 0.79 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL31032211 | 0.77 | UHRF1 (0.50) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL27851285 | 0.77 | UHRF1 (0.50) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL16094048 | 0.77 | UHRF1 (0.50) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL20909890 | 0.76 | UHRF1 (0.42) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL12496906 | 0.76 | UHRF1 (0.42) | UHRF1CCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402982-A | Synthesis of 2-carboxamide cyclosemicarbazide derivatives | NOVARTIS AG | 2013-11-20 | — | — | CN | disclosed |