Creatinine

Creatinine

SCHEMBL435006

CN1CC(=O)NC1=N.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Creatinine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Creatinine SCHEMBL288087 0.98 CRBN (0.61)
Creatinine SCHEMBL8809815 0.98 CRBN (0.61)
Creatinine SCHEMBL7203535 0.98
Creatinine SCHEMBL16295 0.98
Creatinine SCHEMBL6473476 0.95
Creatinine SCHEMBL8637084 0.95
Creatinine SCHEMBL4332495 0.95
Creatinine SCHEMBL2922002 0.95
Creatinine SCHEMBL3514057 0.95
Creatinine SCHEMBL21404081 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798120-A Preparation method of creatine monohydrate 安徽泰格生物科技有限公司 2025-04-11 CN claimed
CN-119798120-A Preparation method of creatine monohydrate 安徽泰格生物科技有限公司 2025-04-11 CN disclosed
CN-222267099-U Be used for creatine monohydrate production synthesizer 宁夏享誉生物科技有限公司 2024-12-31 CN disclosed
CN-118834137-A Novel preparation method of sarcosine and derivatives thereof 潜江永安药业股份有限公司 2024-10-25 CN disclosed
CN-118594603-A Material for reducing impurity content in creatine monohydrate, preparation method and application thereof 宁夏享誉生物科技有限公司 2024-09-06 CN disclosed
CN-112226113-B Film for cleaning tableware, preparation method thereof and tableware film laminating equipment 白江龙 2024-07-09 CN disclosed
CN-115636772-B Preparation method of high-purity creatine monohydrate 安徽泰格生物科技有限公司 2024-05-10 CN disclosed
US-20240148040-A1 METHODS OF REDUCING EXERCISE-INDUCED INJURY OR ENHANCING MUSCLE RECOVERY AFTER EXERCISE TARGET CAPITAL 4 LLC 2024-05-09 US disclosed
CN-117756679-A Method for reducing content of trace and trace impurities in creatine monohydrate 宁夏大学 2024-03-26 CN disclosed
WO-2022115353-A1 METHODS OF REDUCING EXERCISE-INDUCED INJURY OR ENHANCING MUSCLE RECOVERY AFTER EXERCISE INTRINSIC MEDICINE, INC. (US) 2022-06-02 WO disclosed
US-7968581-B2 Imidazolidine compounds as androgen receptor modulators GALAPAGOS NV (BE) 2011-06-28 US disclosed
EP-2319686-A1 DEOXIDIZING LAMINATE Mitsubishi Gas Chemical Company, Inc. (JP) 2011-05-11 EP disclosed
WO-2010103539-A2 SUSTAINED RELEASE ORAL FORMULATION OF VINPOCETINE PATEL DINESH SHANTILAL (IN) 2010-09-16 WO disclosed
US-20100113547-A1 NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AKASHI THERAPEUTICS, INC. 2010-05-06 US disclosed
WO-2010029119-A1 NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS GALAPAGOS NV (BE) 2010-03-18 WO disclosed
WO-2009120182-A2 SULFO-POLYMER POWDER AND SULFO-POLYMER POWDER BLENDS WITH CARRIERS AND/OR ACTIVES EASTMAN CHEMICAL COMPANY (US) 2009-10-01 WO disclosed
US-20090163449-A1 SULFO-POLYMER POWDER AND SULFO-POLYMER POWDER BLENDS WITH CARRIERS AND/OR ADDITIVES EASTMAN CHEMICAL COMPANY (US) 2009-06-25 US disclosed
US-20080311613-A1 ARTIFICIAL SKIN SURFACE FILM LIQUIDS THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES 2008-12-18 US disclosed
US-6617356-B2 Gel system for oral and topical administration of water insoluble and/or water intolerant drugs and supplements NATURALLY SCIENTIFIC, INC. 2003-09-09 US disclosed
US-20010006671-A1 GEL SYSTEM FOR ORAL AND TOPICAL ADMINISTRATION OF WATER INSOLUBLE AND/OR WATER INTOLERANT DRUGS AND SUPPLEMENTS NATURALLY SCIENTIFIC, INC. 2001-07-05 US disclosed