Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112850 | 0.81 | LMNA (0.48) | LMNAPOLBHTTGRM2AURKA | |
| SCHEMBL20639210 | 0.79 | LMNA (0.47) | LMNAPOLBHTTGRM2AURKA | |
| Hydrochloric Acid SCHEMBL17048486 | 0.79 | LMNA (0.47) | LMNAPOLBHTTGRM2AURKA | |
| SCHEMBL19641722 | 0.79 | LMNA (0.47) | LMNAPOLBHTTGRM2AURKA | |
| SCHEMBL23998479 | 0.78 | LMNA (0.55) | LMNAPOLBHTTGRM2AURKA | |
| SCHEMBL23539404 | 0.78 | LMNA (0.45) | LMNAPOLBHTTGRM2AURKA | |
| SCHEMBL687644 | 0.77 | LMNA (0.48) | LMNAPOLBHTTGRM2AURKA | |
| SCHEMBL17344113 | 0.76 | CA12 (0.48) | LMNAL3MBTL1GAAMAPTLCK | |
| SCHEMBL10103467 | 0.75 | GAA (0.47) | LMNAPOLBHTTGRM2AURKA | |
| SCHEMBL1425704 | 0.75 | LMNA (0.42) | LMNAPOLBHTTGRM2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102372728-B | Synthesizing method for cephalosporin compound | QILU ANTIBIOTICS PHARMACEUTICAL CO LTD | 2013-12-11 | — | — | CN | claimed |