Azepane

Azepane

SCHEMBL2880906

C1CCCNCC1.O=C(O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.51
ALDH1A1 P00352 2/20 0.50
CTSD P07339 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 2/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
DTYMK P23919 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azepane SCHEMBL5406898 0.88 TSHR (0.53) TSHRALDH1A1MEN1KMT2ATDP1
Piperidine SCHEMBL27656298 0.87 ALDH1A1 (0.49) ALDH1A1CTSDMEN1KMT2ATDP1
SCHEMBL78205 0.85 TSHR (0.67) TSHRALDH1A1CTSDMEN1KMT2A
SCHEMBL30727560 0.85 TSHR (0.67) TSHRALDH1A1CTSDMEN1KMT2A
SCHEMBL29696138 0.85 TSHR (0.67) TSHRALDH1A1CTSDMEN1KMT2A
Ammonia Solution, Strong SCHEMBL11058598 0.83 TSHR (0.65) TSHRALDH1A1CTSDMEN1KMT2A
SCHEMBL625577 0.83 TSHR (0.65) TSHRALDH1A1CTSDMEN1KMT2A
SCHEMBL6391676 0.83 TSHR (0.65) TSHRALDH1A1CTSDMEN1KMT2A
SCHEMBL9125306 0.83 TSHR (0.65) TSHRALDH1A1CTSDMEN1KMT2A
SCHEMBL4587804 0.83 TSHR (0.65) TSHRALDH1A1CTSDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010537404-A 2010-12-02 JP claimed
EP-2186121-A2 COMPOSITIONS AND METHODS FOR MODIFYING A SURFACE SUITED FOR SEMICONDUCTOR FABRICATION 3M Innovative Properties Company (US) 2010-05-19 EP claimed
WO-2009023387-A2 COMPOSITIONS AND METHODS FOR MODIFYING A SURFACE SUITED FOR SEMICONDUCTOR FABRICATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-02-19 WO claimed
US-20080026583-A1 COMPOSITIONS AND METHODS FOR MODIFYING A SURFACE SUITED FOR SEMICONDUCTOR FABRICATION 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US claimed
US-4051066-A Corrosion-inhibiting rubber and methods of preparation NORTHERN INSTRUMENTS CORPORATION (US) 1977-09-27 US claimed
US-12385591-B2 Volatile corrosion inhibitor detection device GENERAL AIR PRODUCTS, INC. (US) 2025-08-12 US disclosed
US-20220282822-A1 VOLATILE CORROSION INHIBITOR DETECTION DEVICE GENERAL AIR PRODUCTS, INC. (US) 2022-09-08 US disclosed
US-11371643-B2 Corrosion risk reduction apparatus, corrosion risk reduction detection device and corrosion risk reduction systems and methods GENERAL AIR PRODUCTS, INC. (US) 2022-06-28 US disclosed
WO-2022081423-A1 CORROSION RISK REDUCTION APPARATUS, CORROSION RISK REDUCTION DETECTION DEVICE AND CORROSION RISK REDUCTION SYSTEMS AND METHODS GENERAL AIR PRODUCTS, INC. (US) 2022-04-21 WO disclosed
US-20220112977-A1 CORROSION RISK REDUCTION APPARATUS, CORROSION RISK REDUCTION DETECTION DEVICE AND CORROSION RISK REDUCTION SYSTEMS AND METHODS GENERAL AIR PRODUCTS, INC. (US) 2022-04-14 US disclosed
US-8800224-B1 Corrosion inhibiting vapor for use in connection with encased articles CORTEC CORPORATION (US) 2014-08-12 US disclosed
US-4929490-A Window frame rubber moldings for automobile TOYODA GOSEI CO., LTD. (JP) 1990-05-29 US disclosed