Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.44 |
| ▸ | NPY1R | P25929 | 6/20 | 0.44 |
| ▸ | NPY2R | P49146 | 4/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673367 | 0.89 | KISS1R (0.46) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL11302814 | 0.88 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL11302796 | 0.88 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL2876318 | 0.86 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL29732500 | 0.84 | NPY4R (0.56) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL31412176 | 0.82 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL29540098 | 0.81 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL3295134 | 0.81 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL31314356 | 0.81 | NPY4R (0.59) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30798743 | 0.81 | NPY4R (0.60) | NPY4RNPY1RNPY2RNPY5RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8409840-B2 | Recombinant preparation of selected bromelain fractions | URSAPHARM ARZNEIMITTEL GMBH (DE) | 2013-04-02 | — | — | US | disclosed |
| EP-2173868-B1 | RECOMBINANT PREPARATION OF SELECTED BROMELAIN FRACTIONS | URSAPHARM ARZNEIMITTEL GMBH (DE) | 2012-10-17 | — | — | EP | disclosed |
| US-20100272659-A1 | RECOMBINANT PREPARATION OF SELECTED BROMELAIN FRACTIONS | URSAPHARM ARZNEIMITTEL GMBH (DE) | 2010-10-28 | — | — | US | disclosed |
| EP-2173868-A1 | RECOMBINANT PREPARATION OF SELECTED BROMELAIN FRACTIONS | URSAPHARM Arzneimittel GmbH & Co. KG (DE) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009033536-A1 | RECOMBINANT PREPARATION OF SELECTED BROMELAIN FRACTIONS | URSAPHARM ARZNEIMITTEL GMBH & CO. KG (DE) | 2009-03-19 | — | — | WO | disclosed |
| EP-2036978-A1 | Recombinant preparation of selected bromelain fractions | URSAPHARM Arzneimittel GmbH & Co. KG (DE) | 2009-03-18 | — | — | EP | disclosed |