Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875967 | 0.86 | ATM (0.41) | ATMMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10755484 | 0.84 | KDM4E (0.39) | PPARGMAPTALDH1A1HPGDHTT | |
| SCHEMBL1636144 | 0.77 | ATM (0.42) | ATMPPARAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL55069 | 0.77 | ATM (0.42) | ATMMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28382631 | 0.77 | ATM (0.42) | ATMMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5453339 | 0.75 | ATM (0.41) | ATMMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11816303 | 0.75 | ATM (0.41) | ATMPPARAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL8413574 | 0.74 | ATM (0.40) | ATMMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8763459 | 0.74 | ATM (0.44) | ATMPPARGPPARAMAPTL3MBTL1 | |
| SCHEMBL2875061 | 0.72 | ATM (0.39) | ATMPPARGPPARAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |