SCHEMBL5453339

SCHEMBL5453339

CCC(=O)c1cc[c]c(N)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
MAPT P10636 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HPGD P15428 3/20 0.37
ALDH1A1 P00352 2/20 0.37
HTT P42858 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
KDM4E B2RXH2 1/20 0.35
BRAF P15056 1/20 0.34
HSP90AB1 P08238 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CYP3A4 P08684 2/20 0.33
PTGS1 P23219 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3883974 0.86 HSD17B3 (0.46) MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1
SCHEMBL55069 0.79 ATM (0.42) ATMMAPTSMN1; SMN2L3MBTL1HPGD
SCHEMBL1636144 0.79 ATM (0.42) ATMMAPTSMN1; SMN2L3MBTL1HPGD
SCHEMBL28382631 0.79 ATM (0.42) ATMMAPTSMN1; SMN2L3MBTL1HPGD
SCHEMBL11816303 0.78 ATM (0.41) ATMMAPTSMN1; SMN2L3MBTL1HPGD
SCHEMBL2875967 0.78 ATM (0.41) ATMMAPTSMN1; SMN2L3MBTL1HPGD
SCHEMBL8763459 0.76 ATM (0.44) ATMMAPTSMN1; SMN2L3MBTL1HPGD
SCHEMBL8413574 0.76 ATM (0.40) ATMMAPTSMN1; SMN2L3MBTL1HPGD
SCHEMBL444146 0.76 GABRP (0.44) MAPTL3MBTL1HPGDALDH1A1HTT
SCHEMBL27946268 0.76 PARP1 (0.42) MAPTSMN1; SMN2L3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101208341-B Hexarylene and pentarylene tetracarboxylic acid diimides BASF AG 2014-12-10 CN disclosed
CN-103874742-A Carbazolocarbazole-bis (dicarboximides) and their use as semiconductors BASF SE 2014-06-18 CN disclosed
CN-101809116-B Halogen-containing perylene tetracarboxylic acid derivatives and uses thereof BASF SE 2014-03-19 CN disclosed
CN-101573414-B Pentarylene and hexarylene tetracarboxylic acid diimides, and production thereof BASF SE 2014-01-15 CN disclosed
CN-102066374-A Threefold and fourfold substituted pentarylene tetracarboxylic acid diimides BASF SE 2011-05-18 CN disclosed
CN-102057015-A Chlorinated naphthalenetetracarboxylic acid derivatives, preparation thereof and use thereof in organic electronics BASF SE 2011-05-11 CN disclosed
CN-101068810-B Carbostyril compound OTSUKA PHARMA CO LTD 2011-02-09 CN disclosed
CN-101809116-A Halogen-containing perylene tetracarboxylic acid derivatives and uses thereof BASF SE 2010-08-18 CN disclosed
CN-100586949-C Method for producing quaterrylene-3,4:13,14-tetracarboxy diimides by direct synthesis BASF AG 2010-02-03 CN disclosed
CN-101573414-A Pentarylene and hexarylene tetracarboxylic acid diimides, and production thereof BASF SE (DE) 2009-11-04 CN disclosed
CN-1633472-A Thermochromic rylene dyes BASF AG (DE) 2005-06-29 CN disclosed
CN-1155576-C Thermochromic rylene dyes �����ɷ� 2004-06-30 CN disclosed
CN-1492858-A Pylene derivatives and their use as dyes �����ɷ� 2004-04-28 CN disclosed
CN-1092197-C Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-10-09 CN disclosed
CN-1371368-A Thermochromic rylene dyes BASF AG (DE) 2002-09-25 CN disclosed
CN-1091123-C Process for producing and purifying perylene-3,4-dicarboxylic acid imides BASF AG (DE) 2002-09-18 CN disclosed
CN-1200114-A Quinoline derivatives as GNRH antagonists TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-11-25 CN disclosed
CN-1168151-A Process for producing and purifying perylene-3,4-dicarboxylic acid imides BASF AG (DE) 1997-12-17 CN disclosed
CN-1146206-A Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-03-26 CN disclosed
EP-0281045-A1 Benzothiepino (5,4-c) pyridazine compounds and their pharmaceutical uses Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1988-09-07 EP disclosed