Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123882 | 1.00 | KDM4E (0.33) | KDM4EHCAR3MCL1MEN1KMT2A | |
| SCHEMBL31729301 | 1.00 | KDM4E (0.33) | KDM4EHCAR3MCL1MEN1KMT2A | |
| SCHEMBL31728984 | 0.84 | ELANE (0.39) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL23563020 | 0.83 | KDM4E (0.33) | KDM4EHCAR3MCL1MEN1KMT2A | |
| SCHEMBL31704421 | 0.83 | KDM4E (0.33) | KDM4EHCAR3MCL1MEN1KMT2A | |
| SCHEMBL29753942 | 0.82 | MEN1 (0.44) | KDM4EMCL1MEN1KMT2AMAPK8 | |
| SCHEMBL23563223 | 0.79 | KDM4E (0.39) | KDM4EMEN1KMT2ARAB9AMAPT | |
| SCHEMBL8320853 | 0.74 | NAMPT (0.40) | KDM4EMEN1KMT2AMAPK1MAPT | |
| SCHEMBL30910209 | 0.73 | — | — | |
| SCHEMBL16493936 | 0.72 | RXFP1 (0.37) | KDM4EMCL1MAPK8APOBEC3ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |