Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9792756 | 0.79 | PRSS1 (0.50) | F2F10F7F12F3 | |
| SCHEMBL27893662 | 0.76 | ASIC3 (0.56) | MAPK14HSP90AA1HSP90AB1CYP19A1GRM5 | |
| SCHEMBL9792777 | 0.76 | PRSS1 (0.61) | F2PRSS1PRSS2PRSS3C1S | |
| SCHEMBL2410176 | 0.76 | KDM4C (0.60) | PKMKDM4CMAPK14KMT2A | |
| SCHEMBL14226702 | 0.76 | KDM4C (0.48) | KDM4CKMT2AMAPKAPK2 | |
| SCHEMBL14241385 | 0.76 | KDM4C (0.48) | KDM4CMAPK14MAPKAPK2 | |
| SCHEMBL5673245 | 0.75 | CCR1 (0.46) | PKMMAPK14HSP90AA1HSP90AB1CYP19A1 | |
| SCHEMBL2435961 | 0.73 | RECQL (0.44) | F2F10F12PRSS1PRSS2 | |
| SCHEMBL27945042 | 0.73 | CYP1A2 (0.49) | MAPK14HSP90AA1HSP90AB1CYP19A1 | |
| SCHEMBL4766667 | 0.73 | JMJD6 (0.58) | KDM4CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429583-A | Triazole derivatives as WNT signaling pathway inhibitors | OSLO UNIVERSITY HOSPITAL HF | 2013-12-04 | — | — | CN | disclosed |