Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.60 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597699 | 0.90 | KMT2A (0.90) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL30101230 | 0.90 | KMT2A (0.90) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL4548162 | 0.88 | KMT2A (0.87) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL17664317 | 0.85 | KMT2A (0.81) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL30069239 | 0.85 | MAPT (1.00) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL17609423 | 0.85 | MAPT (1.00) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL26416486 | 0.85 | MAPT (0.76) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL14459434 | 0.84 | KMT2A (0.74) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL966454 | 0.83 | ALDH1A1 (1.00) | MAPTKMT2AMEN1HTTRAB9A | |
| SCHEMBL2632866 | 0.83 | MAPT (0.73) | MAPTKMT2AMEN1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570723-A | Pyrazolopyrimidine derivative, its preparation method, and its use in preparation of medicines | UNIV SICHUAN | 2014-02-12 | — | — | CN | disclosed |