Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000504 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL21044536 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL27942428 | 0.81 | PDE5A (0.37) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9390231 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL999516 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL11972348 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL9481200 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL27466229 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL5250136 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL999180 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664897-A | Dihydropyrimidine compounds and application thereof in medicines | GUANGDONG HEC PHARMACEUTICAL | 2014-03-26 | — | — | CN | disclosed |