Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12761295 | 0.86 | ABCB1 (0.36) | ABCB1OPRM1OPRL1 | |
| SCHEMBL28810670 | 0.77 | DHODH (0.33) | DHODHOPRM1OPRL1 | |
| SCHEMBL23148165 | 0.77 | — | — | |
| SCHEMBL28809785 | 0.76 | OPRL1 (0.34) | DHODHOPRM1OPRL1 | |
| SCHEMBL28810746 | 0.76 | DHODH (0.32) | DHODHOPRM1OPRL1 | |
| SCHEMBL28183722 | 0.68 | DRD2 (0.33) | — | |
| SCHEMBL28810413 | 0.67 | CDK5 (0.33) | — | |
| SCHEMBL28810629 | 0.66 | DHODH (0.32) | DHODH | |
| SCHEMBL28809727 | 0.64 | DHODH (0.31) | DHODH | |
| SCHEMBL20689200 | 0.64 | DHODH (0.40) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |