Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.49 |
| ▸ | WNT1 | P04628 | 4/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28809213 | 1.00 | KDM1A (0.51) | KDM1ADYRK1AWNT1BACE1ALDH1A1 | |
| SCHEMBL29753995 | 1.00 | KDM1A (0.51) | KDM1ADYRK1AWNT1BACE1ALDH1A1 | |
| SCHEMBL28809212 | 1.00 | KDM1A (0.51) | KDM1ADYRK1AWNT1BACE1ALDH1A1 | |
| SCHEMBL28811003 | 0.92 | DYRK1A (0.51) | KDM1ADYRK1AWNT1BACE1ALDH1A1 | |
| SCHEMBL28811002 | 0.92 | DYRK1A (0.51) | KDM1ADYRK1AWNT1BACE1ALDH1A1 | |
| SCHEMBL28809202 | 0.90 | BACE1 (0.60) | DYRK1AWNT1BACE1ALDH1A1KMT2A | |
| SCHEMBL29754069 | 0.90 | BACE1 (0.60) | DYRK1AWNT1BACE1ALDH1A1KMT2A | |
| SCHEMBL23533891 | 0.90 | HTR4 (0.56) | KDM1ADYRK1AWNT1BACE1ALDH1A1 | |
| SCHEMBL29753901 | 0.90 | HTR4 (0.56) | KDM1ADYRK1AWNT1BACE1ALDH1A1 | |
| SCHEMBL28810225 | 0.88 | DYRK1A (0.48) | KDM1ADYRK1AWNT1BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |