Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23302103 | 0.86 | PBRM1 (0.52) | — | |
| SCHEMBL23301263 | 0.84 | KCNH2 (0.43) | OPRD1KCNH2HSD11B1MEN1KMT2A | |
| SCHEMBL29943255 | 0.83 | OPRD1 (0.51) | OPRD1KCNH2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23301640 | 0.83 | OPRD1 (0.51) | OPRD1KCNH2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29943128 | 0.82 | CKS1B (0.42) | OPRD1KCNH2HSD11B1KMT2ACNR1 | |
| SCHEMBL23037203 | 0.81 | PBRM1 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28810427 | 0.81 | SMARCA2 (0.54) | OPRD1KCNH2HSD11B1TSHR | |
| SCHEMBL29943226 | 0.81 | SMARCA2 (0.54) | OPRD1KCNH2HSD11B1TSHR | |
| SCHEMBL23301272 | 0.77 | SMARCA2 (0.47) | OPRD1KCNH2HSD11B1TSHR | |
| SCHEMBL29942944 | 0.77 | SMARCA2 (0.47) | OPRD1KCNH2HSD11B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728936-A | Bifunctional compounds for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2022-07-08 | — | — | CN | disclosed |