Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810287 | 0.86 | WNT1 (0.52) | WNT1DYRK1AUSP30HDAC4MEN1 | |
| SCHEMBL23534247 | 0.84 | WNT1 (0.54) | WNT1DYRK1AUSP30HDAC4MEN1 | |
| SCHEMBL29753981 | 0.83 | KDM1A (0.54) | WNT1DYRK1AALOX5AP | |
| SCHEMBL28810993 | 0.83 | KDM1A (0.54) | WNT1DYRK1AALOX5AP | |
| SCHEMBL29753928 | 0.81 | WNT1 (0.47) | WNT1DYRK1AUSP30MEN1ALDH1A1 | |
| SCHEMBL23533897 | 0.81 | DYRK1A (0.74) | WNT1DYRK1A | |
| SCHEMBL29754004 | 0.81 | DYRK1A (0.74) | WNT1DYRK1A | |
| SCHEMBL23534341 | 0.77 | DYRK1A (0.69) | WNT1DYRK1AUSP30 | |
| SCHEMBL2071421 | 0.73 | TP53 (0.52) | USP30HDAC4MEN1ALDH1A1KMT2A | |
| SCHEMBL23360639 | 0.71 | PARP1 (0.59) | USP30HDAC4MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |