SCHEMBL28811110

SCHEMBL28811110

Nc1c(N)c(N)c(C(=O)O)c(O)c1N

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
G6PD P11413 1/20 0.33
CASP7 P55210 1/20 0.33
CASP6 P55212 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33
MMP2 P08253 1/20 0.33
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33
CYP1A2 P05177 1/20 0.32
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19775119 0.78 DPP4 (0.36) DPP4CA12CA1CA2CA7
SCHEMBL8605888 0.76 GLRA3 (0.37) DPP4CA12CA1CA2CA7
SCHEMBL7266193 0.76 CYP1A2 (0.38) DPP4CA12CA1CA2CA7
SCHEMBL28397803 0.72 CYP1A2 (0.40) DPP4CA12CA1CA2CA7
SCHEMBL7058324 0.72 CYP1A2 (0.40) DPP4CA12CA1CA2CA7
SCHEMBL23164220 0.68 GLRA3 (0.48) DPP4CA12CA1CA2CA7
SCHEMBL13586980 0.68 DPP4 (0.46) DPP4CA12CA1CA2CA7
SCHEMBL28343560 0.68 GLRA3 (0.48) DPP4CA12CA1CA2CA7
SCHEMBL27121360 0.67 KDM4E (0.44) DPP4CA12CA1CA2CA7
SCHEMBL11440009 0.67 THRB (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118186392-A Method for preparing corrosion inhibitor by taking coal tar pitch as carbon point and application thereof 河南理工大学 2024-06-14 CN disclosed
CN-114875411-A Asphalt-based carbon dot corrosion inhibitor and preparation method and application thereof 河南理工大学 2022-08-09 CN disclosed