Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28924888 | 0.97 | LMNA (0.36) | LMNADNM1 | |
| Hydrochloric Acid SCHEMBL691763 | 0.97 | LMNA (0.39) | LMNADNM1NFKB1 | |
| Bromide SCHEMBL10785570 | 0.97 | LMNA (0.39) | LMNADNM1NFKB1 | |
| Bromide SCHEMBL28218539 | 0.95 | LMNA (0.38) | LMNADNM1NFKB1 | |
| Hydrochloric Acid SCHEMBL9471263 | 0.95 | LMNA (0.38) | LMNADNM1NFKB1 | |
| Hydrochloric Acid SCHEMBL3754407 | 0.95 | LMNA (0.38) | LMNADNM1NFKB1 | |
| Hydrochloric Acid SCHEMBL3754410 | 0.95 | LMNA (0.38) | LMNADNM1NFKB1 | |
| Hydrochloric Acid SCHEMBL28033338 | 0.95 | LMNA (0.38) | LMNADNM1NFKB1 | |
| SCHEMBL9491840 | 0.95 | LMNA (0.40) | LMNADNM1NFKB1 | |
| SCHEMBL15124 | 0.95 | LMNA (0.40) | LMNADNM1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114873606-A | Preparation method and application of acidic hierarchical pore MFI structure molecular sieve | 华东理工大学 | 2022-08-09 | — | — | CN | claimed |
| CN-114873606-A | Preparation method and application of acidic hierarchical pore MFI structure molecular sieve | 华东理工大学 | 2022-08-09 | — | — | CN | disclosed |