Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860483 | 1.00 | ATM (0.42) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL21750020 | 0.89 | ATM (0.44) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL21749937 | 0.81 | HCAR2 (0.41) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL31394030 | 0.81 | ATM (0.50) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL28194744 | 0.81 | TSHR (0.43) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL17802090 | 0.80 | ALDH1A1 (0.43) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL10467534 | 0.79 | ALDH1A1 (0.48) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL31184958 | 0.79 | ATM (0.44) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL9939057 | 0.79 | ATM (0.44) | ATMKDM4EALDH1A1GAAGLA | |
| SCHEMBL16694522 | 0.79 | GAA (0.42) | ATMKDM4EALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291065-B | Novel isoindoline derivative, pharmaceutical composition and application thereof | 康朴生物医药技术（上海）有限公司 | 2022-08-19 | — | — | CN | disclosed |