Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28831226 | 0.84 | MCHR1 (0.41) | MCHR1BACE1 | |
| SCHEMBL28257280 | 0.81 | MEN1 (0.54) | ADORA2AADORA1PTGS2PTGS1MEN1 | |
| SCHEMBL27971605 | 0.77 | MCHR1 (0.57) | MCHR1BACE1KMT2AHRH4 | |
| SCHEMBL1655715 | 0.73 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL5305206 | 0.73 | PTGS2 (0.53) | ADORA2AADORA1PTGS2PTGS1MEN1 | |
| SCHEMBL28158819 | 0.72 | MCHR1 (0.49) | MCHR1BACE1MEN1KMT2A | |
| SCHEMBL25129319 | 0.72 | PTGS2 (0.63) | ADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL31074324 | 0.72 | PTGS2 (0.63) | ADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL3352381 | 0.71 | MCHR1 (0.47) | MCHR1BACE1MEN1KMT2A | |
| SCHEMBL3809264 | 0.71 | MCHR1 (0.47) | MCHR1BACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105530938-A | Compounds for the treatment of diseases caused by retroviruses | ABIVAX | 2016-04-27 | — | — | CN | claimed |
| CN-104945378-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX | 2015-09-30 | — | — | CN | claimed |
| CN-103948594-B | Compounds for the treatment of cancer | ABIVAX公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-105530938-A | Compounds for the treatment of diseases caused by retroviruses | ABIVAX | 2016-04-27 | — | — | CN | disclosed |
| CN-104945378-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX | 2015-09-30 | — | — | CN | disclosed |
| CN-104945379-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX | 2015-09-30 | — | — | CN | disclosed |
| CN-104844570-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX | 2015-08-19 | — | — | CN | disclosed |
| CN-104844510-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX | 2015-08-19 | — | — | CN | disclosed |
| CN-102625804-B | Compounds for the treatment of AIDS | ABIVAX | 2015-04-08 | — | — | CN | disclosed |
| CN-102596935-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX CORP | 2015-02-18 | — | — | CN | disclosed |
| CN-103948594-A | Compounds for the treatment of cancer | SPLICOS SOC | 2014-07-30 | — | — | CN | disclosed |
| CN-102574835-B | Compounds for the treatment of cancer | SPLICOS SOC | 2014-04-16 | — | — | CN | disclosed |