⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778567 | 0.79 | — | — | |
| SCHEMBL28812268 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL14779669 | 0.77 | MAPK1 (0.32) | — | |
| SCHEMBL14778185 | 0.75 | — | — | |
| SCHEMBL28982588 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL28276847 | 0.75 | MAPK1 (0.31) | — | |
| SCHEMBL11303039 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL10482216 | 0.73 | TSHR (0.34) | — | |
| SCHEMBL14777520 | 0.72 | — | — | |
| SCHEMBL28173577 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613414-A | Non-azolanet Process for the preparation of tam | 上海皓元医药股份有限公司 | 2025-03-14 | — | — | CN | claimed |
| US-12059467-B2 | Low-toxicity and high-efficiency orthoester mixture pharmaceutical adjuvant, preparation method thereof, and topical sustained release drug delivery formulation including same | ANHUI UNIVERSITY (CN) | 2024-08-13 | — | — | US | claimed |
| US-20240108728-A1 | IMPROVED LOW-TOXICITY AND HIGH-EFFICIENCY ORTHOESTER MIXTURE PHARMACEUTICAL ADJUVANT, PREPARATION METHOD THEREOF, AND TOPICAL SUSTAINED RELEASE DRUG DELIVERY FORMULATION INCLUDING SAME | ANHUI UNIVERSITY (CN) | 2024-04-04 | — | — | US | claimed |
| WO-2023221320-A1 | IMPROVED LOW-TOXICITY AND HIGHLY EFFICIENT PHARMACEUTICAL EXCIPIENT OF ORTHOESTER MIXTURE, METHOD FOR PREPARING SAME, AND LOCAL SUSTAINED-RELEASE PREPARATION COMPRISING SAME | 安徽大学 | 2023-11-23 | — | — | WO | claimed |
| CN-114848585-A | Improved low-toxicity high-efficiency orthoester miscible medicine pharmaceutic adjuvant, preparation method and local sustained-release administration preparation containing adjuvant | 安徽大学 | 2022-08-05 | — | — | CN | claimed |
| CN-119613414-A | Non-azolanet Process for the preparation of tam | 上海皓元医药股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2023221320-A1 | IMPROVED LOW-TOXICITY AND HIGHLY EFFICIENT PHARMACEUTICAL EXCIPIENT OF ORTHOESTER MIXTURE, METHOD FOR PREPARING SAME, AND LOCAL SUSTAINED-RELEASE PREPARATION COMPRISING SAME | 安徽大学 | 2023-11-23 | — | — | WO | disclosed |
| CN-114848585-A | Improved low-toxicity high-efficiency orthoester miscible medicine pharmaceutic adjuvant, preparation method and local sustained-release administration preparation containing adjuvant | 安徽大学 | 2022-08-05 | — | — | CN | disclosed |