Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ATIC | P31939 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799756 | 0.81 | CDK2 (0.42) | CDK2KAT6ASTAT3MAOATDP1 | |
| SCHEMBL4605735 | 0.81 | CDK2 (0.42) | CDK2KAT6ASTAT3MAOATDP1 | |
| SCHEMBL229902 | 0.80 | PTGES2 (0.46) | CDK2TTRKAT6AMYCFABP4 | |
| Hydrochloric Acid SCHEMBL27565435 | 0.78 | PTGES2 (0.45) | CDK2TTRKAT6AMYCFABP4 | |
| SCHEMBL27710538 | 0.77 | STAT3 (0.55) | AURKAAURKBCDK2TTRSTAT3 | |
| SCHEMBL114040 | 0.77 | CDK2 (0.50) | AURKAAURKBCDK2TTRSTAT3 | |
| SCHEMBL29470806 | 0.77 | CDK2 (0.50) | AURKAAURKBCDK2TTRSTAT3 | |
| SCHEMBL359454 | 0.77 | AURKA (0.47) | AURKAAURKBCDK2TTRSTAT3 | |
| SCHEMBL28837410 | 0.77 | TTR (0.60) | AURKAAURKBTTRCYP1A2MYC | |
| Phenolsulphonic Acid SCHEMBL11154671 | 0.77 | SMN1; SMN2 (0.46) | AURKAAURKBCDK2TTRCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736156-A | Preparation method and application of simplified derivatives of cryptolepine | 中捷四方生物科技股份有限公司 | 2022-07-12 | — | — | CN | disclosed |