SCHEMBL229902

SCHEMBL229902

O=S(=O)(O)c1cccc(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGES2 Q9H7Z7 2/20 0.46
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
BCHE P06276 1/20 0.45
AKR1B1 P15121 1/20 0.45
TTR P02766 2/20 0.44
MYC P01106 1/20 0.37
KAT6A Q92794 4/20 0.37
PKM P14618 1/20 0.36
PKLR P30613 1/20 0.36
FABP4 P15090 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
MAPK14 Q16539 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.35
NR4A1 P22736 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27565435 0.98 PTGES2 (0.45) PTGES2CES2CES1BCHEAKR1B1
SCHEMBL778163 0.82 PTGES2 (0.41) PTGES2CES2CES1BCHEAKR1B1
SCHEMBL152363 0.82 PKM (0.45) PTGES2CES2CES1BCHEAKR1B1
SCHEMBL778219 0.81 AKR1B1 (0.56) PTGES2CES2CES1BCHEAKR1B1
SCHEMBL231071 0.81 KAT6A (0.46) CES2CES1AKR1B1TTRMYC
SCHEMBL30476135 0.81 KAT6A (0.46) CES2CES1AKR1B1TTRMYC
SCHEMBL29860559 0.81 AKR1B1 (0.56) PTGES2CES2CES1BCHEAKR1B1
SCHEMBL28811695 0.80 AURKA (0.44) TTRMYCKAT6AFABP4CCNA2
SCHEMBL8379679 0.79 KAT6A (0.44) CES2CES1AKR1B1TTRMYC
SCHEMBL8376433 0.79 KAT6A (0.44) CES2CES1AKR1B1TTRMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115151591-B Composition, cured product, and method for producing cured product 株式会社艾迪科 2024-03-01 CN disclosed
CN-111699204-B Radical polymerization initiator, composition containing the same, cured product thereof, method for producing the same, and compound 株式会社ADEKA 2023-07-21 CN disclosed
US-11618742-B2 Radical polymerization initiator, composition containing same, cured product of composition, production method for cured product, and compound ADEKA CORPORATION (JP) 2023-04-04 US disclosed
US-11591308-B2 2023-02-28 US disclosed
CN-115151591-A Composition, cured product, and method for producing cured product 株式会社艾迪科 2022-10-04 CN disclosed
CN-114502608-A Polymerizable composition, carrier, cured product, and method for producing same 株式会社ADEKA 2022-05-13 CN disclosed
US-20210107887-A1 RADICAL POLYMERIZATION INITIATOR, COMPOSITION CONTAINING SAME, CURED PRODUCT OF COMPOSITION, PRODUCTION METHOD FOR CURED PRODUCT, AND COMPOUND ADEKA CORPORATION (JP) 2021-04-15 US disclosed
EP-3753958-A1 RADICAL POLYMERIZATION INITIATOR, COMPOSITION CONTAINING SAME, CURED PRODUCT OF COMPOSITION, PRODUCTION METHOD FOR CURED PRODUCT, AND COMPOUND ADEKA CORPORATION (JP) 2020-12-23 EP disclosed
CN-111699204-A Radical polymerization initiator, composition containing the same, cured product thereof, method for producing the same, and compound 株式会社ADEKA 2020-09-22 CN disclosed
US-10538533-B2 Heteroaryls and uses thereof MILLENNIUM PHARMACEUTICALS, INC. (US) 2020-01-21 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed
US-20030235779-A1 Photoacid generating compounds, chemically amplified positive resist materials, and pattern forming method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-12-25 US disclosed
US-20030207201-A1 Photoacid generating compounds, chemically amplified positive resist materials, and pattern forming method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-11-06 US disclosed
US-6602647-B2 Photo acid generator with high transparency and excellent heat stability in a photoresist for lithography using far ultraviolet light, especially light of ArF excimer consists of a cyclic sulfonium compound with 2-oxo group NEC CORPORATION (JP) 2003-08-05 US disclosed
US-20030113659-A1 Resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-06-19 US disclosed
US-20020090569-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-07-11 US disclosed
US-20020045122-A1 Sulfonium salt compound and resist composition and pattern forming method using the same NEC CORPORATION 2002-04-18 US disclosed
EP-1113334-A1 Sulfonium salt compound, resist composition comprising the same and pattern forming method using the composition NEC CORPORATION (JP) 2001-07-04 EP disclosed
US-4278561-A MONITORING SHELF LIFE OF PERISHABLES, POLYMERIZATION, COLOR CHANGE ALLIED CHEMICAL CORPORATION (US) 1981-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591308-B2 RER1, CBR1, H1-10 PTGES2 394/4885CES2 777/4885CES1 1154/4885
US-11618742-B2 Radical polymerization initiator, composition containing same, cured product of composition, production method for cured product, and compound ASH2L, RER1, BOLA2; BOLA2B PTGES2 247/4885CES2 945/4885CES1 1272/4885
US-20030207201-A1 Photoacid generating compounds, chemically amplified positive resist materials, and pattern forming method ASIC1, PARG, EEF1A2 PTGES2 3782/4885CES2 3936/4885CES1 4664/4885
US-10538533-B2 Heteroaryls and uses thereof VPS35, VPS4B, VPS26B PTGES2 4512/4885CES2 3046/4885CES1 847/4885
US-20210107887-A1 RADICAL POLYMERIZATION INITIATOR, COMPOSITION CONTAINING SAME, CURED PRODUCT OF COMPOSITION, PRODUCTION METHOD FOR CURED PRODUCT, AND COMPOUND RRP12, ASH2L, RER1 PTGES2 83/4885CES2 380/4885CES1 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.