Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290755 | 0.86 | KDM4E (0.55) | ALDH1A1MAPTHTTSMYD3GRIN1 | |
| SCHEMBL17591942 | 0.84 | SMYD3 (0.62) | CRBNSMYD3 | |
| SCHEMBL6832459 | 0.82 | SYK (0.57) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL12431387 | 0.82 | SMYD3 (0.59) | ALDH1A1HTTCRBNSMYD3 | |
| SCHEMBL16047746 | 0.82 | CRBN (0.58) | MAPTHTTCRBNDDB1PTPN2 | |
| SCHEMBL30847573 | 0.82 | CRBN (0.58) | MAPTHTTCRBNDDB1PTPN2 | |
| SCHEMBL13586867 | 0.81 | POLB (0.52) | MAPTSMYD3GRIN1GRIN2BGRIN2D | |
| SCHEMBL10269535 | 0.81 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL12853755 | 0.78 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL4115820 | 0.78 | ALDH1A1 (0.77) | ALDH1A1NPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107072205-B | SMYD inhibitors | EPIZYME股份有限公司 | 2022-07-15 | — | — | CN | disclosed |