Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.74 |
| ▸ | IL6 | P05231 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354128 | 1.00 | TNF (0.74) | TNFIL6ALDH1A1HTTCYP24A1 | |
| SCHEMBL14120494 | 0.86 | TNF (0.73) | TNFIL6ALDH1A1HTTCYP24A1 | |
| SCHEMBL14119825 | 0.85 | TNF (1.00) | TNFIL6ALDH1A1CYP24A1MYC | |
| SCHEMBL14119823 | 0.85 | TNF (1.00) | TNFIL6ALDH1A1CYP24A1MYC | |
| SCHEMBL28211054 | 0.80 | TNF (0.68) | TNFIL6CYP24A1MYCMAX | |
| SCHEMBL3438486 | 0.78 | IKBKB (0.57) | TNFIL6ALDH1A1HTTHPGD | |
| SCHEMBL3438488 | 0.78 | IKBKB (0.57) | TNFIL6ALDH1A1HTTHPGD | |
| SCHEMBL26931378 | 0.77 | TNF (0.60) | TNFIL6ALDH1A1CYP24A1MYC | |
| SCHEMBL28426523 | 0.77 | IKBKB (0.56) | TNFIL6ALDH1A1HTTHPGD | |
| SCHEMBL28426522 | 0.77 | IKBKB (0.56) | TNFIL6ALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853630-A | 2, 6-diphenylmethylene cyclohexanone oxime compound and preparation method and application thereof | 温州医科大学 | 2022-08-05 | — | — | CN | claimed |
| CN-114853630-B | 2, 6-benzhydryl cyclohexanone oxime compound and preparation method and application thereof | 温州医科大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-114853630-A | 2, 6-diphenylmethylene cyclohexanone oxime compound and preparation method and application thereof | 温州医科大学 | 2022-08-05 | — | — | CN | disclosed |