Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.57 |
| ▸ | RAF1 | P04049 | 1/20 | 0.57 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | AKT2 | P31751 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.57 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.57 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.57 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.57 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | IL6 | P05231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438486 | 1.00 | IKBKB (0.57) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL28426523 | 0.98 | IKBKB (0.56) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL28426522 | 0.98 | IKBKB (0.56) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL28010017 | 0.96 | IKBKB (0.60) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL28426543 | 0.96 | IKBKB (0.60) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL28009929 | 0.81 | MAPT (0.53) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL3438542 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTTEGFRTNFIL6 | |
| SCHEMBL3438544 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTTEGFRTNFIL6 | |
| SCHEMBL3438081 | 0.79 | DYRK2 (0.57) | DYRK2ALDH1A1HTTEGFRACHE | |
| SCHEMBL3438487 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HTTEGFRACHETNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409845-B2 | Alpha-(3,5-dimethoxybenzylidene)-alpha′-hydrocarbyl methylene cyclic ketone and preparation method thereof | PHARMAXYN LABORATORIES LTD. (CN) | 2016-08-09 | — | — | US | disclosed |
| US-20150259271-A1 | alpha-(3,5-dimethoxybenzylidene)-alpha'-hydrocarbyl methylene cyclic ketone and preparation method thereof | PHARMAXYN LABORATORIES LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| US-7807856-B2 | Process for production of 2-Benzylphenol compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1810957-A1 | METHOD FOR PRODUCING 2-BENZYLPHENOL COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2007-07-25 | — | — | EP | disclosed |
| WO-1998022442-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIARYL-CYCLOMETHYLENPYRAZOLE COMPOUNDS AND THEIR USE AS CYCLOOXYGENASE I (COX 1) INHIBITORS | ANGELINI RICERCHE S.P.A. SOCIETA' CONSORTILE (IT) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | CYP1B1, CYP4B1, CYP1A1 | IKBKB 2487/4885RAF1 921/4885RPS6KB1 100/4885 |
| US-20150259271-A1 | alpha-(3,5-dimethoxybenzylidene)-alpha'-hydrocarbyl methylene cyclic ketone and preparation method thereof | EGFR, KDR, BMI1 | IKBKB 387/4885RAF1 410/4885RPS6KB1 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.