Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16272071 | 0.86 | GPR119 (0.53) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL28646427 | 0.86 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL28812661 | 0.86 | GPR119 (0.54) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL1977326 | 0.85 | GPR119 (0.50) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL21381792 | 0.85 | HTT (0.51) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL14240401 | 0.85 | GPR119 (0.50) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL29090670 | 0.83 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL5472808 | 0.83 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL28341565 | 0.83 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBHTT | |
| SCHEMBL15939961 | 0.83 | GPR119 (0.50) | GPR119KDM4EMAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867720-A | Heteroaryl derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-08-05 | — | — | CN | disclosed |