Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THPO | P40225 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionamide SCHEMBL27534679 | 0.81 | TDP1 (0.40) | TSHRTHPOTDP1CYP1A2CYP2C19 | |
| Cystamine SCHEMBL31646100 | 0.80 | TSHR (0.62) | TSHRTHPOTDP1MAPTEHMT2 | |
| Cystamine SCHEMBL445194 | 0.80 | TSHR (0.62) | TSHRTHPOTDP1MAPTEHMT2 | |
| Cystamine SCHEMBL9753048 | 0.79 | TDP1 (0.58) | TSHRTHPOTDP1MAPTEHMT2 | |
| SCHEMBL5458497 | 0.79 | — | — | |
| Cystamine SCHEMBL9187228 | 0.78 | TSHR (0.59) | TSHRTHPOTDP1MAPTEHMT2 | |
| Propionamide SCHEMBL17165126 | 0.77 | — | — | |
| Cystamine SCHEMBL9417963 | 0.77 | TSHR (0.67) | TSHRTHPOTDP1MAPTEHMT2 | |
| Propionamide SCHEMBL7648033 | 0.76 | — | — | |
| Cystamine SCHEMBL27901365 | 0.76 | TSHR (0.77) | TSHRTHPOTDP1MAPTEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874353-B | Non-viral gene drug carrier based on chitosan oligosaccharide and preparation method thereof | 常州大学 | 2023-01-17 | — | — | CN | claimed |
| CN-114874353-A | Non-viral gene drug carrier based on chitosan oligosaccharide and preparation method thereof | 常州大学 | 2022-08-09 | — | — | CN | claimed |
| CN-114874353-B | Non-viral gene drug carrier based on chitosan oligosaccharide and preparation method thereof | 常州大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114874353-A | Non-viral gene drug carrier based on chitosan oligosaccharide and preparation method thereof | 常州大学 | 2022-08-09 | — | — | CN | disclosed |