Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | THPO | P40225 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cystamine SCHEMBL445194 | 0.80 | TSHR (0.62) | TDP1THPOCYP1A2CYP2C19LMNA | |
| Cystamine SCHEMBL31646100 | 0.80 | TSHR (0.62) | TDP1THPOCYP1A2CYP2C19LMNA | |
| SCHEMBL5458497 | 0.79 | — | — | |
| Cystamine SCHEMBL28812191 | 0.79 | TSHR (0.53) | TDP1THPOCYP1A2CYP2C19LMNA | |
| Cystamine SCHEMBL9417963 | 0.77 | TSHR (0.67) | TDP1THPOCYP1A2CYP2C19LMNA | |
| Iodoacetamide SCHEMBL1332134 | 0.76 | — | — | |
| Iodoacetamide SCHEMBL20371 | 0.76 | — | — | |
| Iodoacetamide SCHEMBL31146774 | 0.76 | — | — | |
| SCHEMBL7882871 | 0.73 | TSHR (0.40) | TDP1THPOTSHRMAPTEHMT2 | |
| Iodoacetamide SCHEMBL25246804 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010427-A2 | THE EFFECT OF TRANSGLUTAMINASE INHIBITION ON MICROFILARIAE DEVELOPMENT AND MACROFILARIAE VIABILITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-07-25 | — | — | WO | claimed |