Acetone

Acetone

SCHEMBL28812412

C=C(C)c1ccccc1.CC(C)=O

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.54
CES2 O00748 4/20 0.54
MAPT P10636 4/20 0.50
TSHR P16473 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
XBP1 P17861 1/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 1/20 0.50
AKT1 P31749 1/20 0.46
CYP3A4 P08684 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
POLB P06746 1/20 0.46
PARP1 P09874 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28207460 0.95 CES1 (0.54) CES1CES2MAPTTSHRSMN1; SMN2
Bicarbonate SCHEMBL9635818 0.95 CES1 (0.54) CES1CES2MAPTTSHRSMN1; SMN2
Bicarbonate SCHEMBL8433139 0.95 CES1 (0.54) CES1CES2MAPTTSHRSMN1; SMN2
Bicarbonate SCHEMBL9637203 0.95 CES1 (0.54) CES1CES2MAPTTSHRSMN1; SMN2
SCHEMBL2905282 0.92
SCHEMBL6577 0.92
SCHEMBL472891 0.92 CES2 (0.48) CES1CES2MAPTTSHRSMN1; SMN2
Hydrogen Peroxide SCHEMBL7249472 0.92 CES2 (0.48) CES1CES2MAPTTSHRSMN1; SMN2
SCHEMBL1331472 0.92
Benzene SCHEMBL28197619 0.92 CES2 (0.48) CES1CES2MAPTTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104151129-A Alpha-methyl styrene selective hydrogenation method CHINA PETROLEUM & CHEMICAL 2014-11-19 CN disclosed