Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779513 | 0.91 | USP2 (0.75) | USP2ALDH1A1KDM4EPOLBANPEP | |
| SCHEMBL457031 | 0.91 | USP2 (0.75) | USP2ALDH1A1KDM4EPOLBANPEP | |
| SCHEMBL2780188 | 0.91 | USP2 (0.75) | USP2ALDH1A1KDM4EPOLBANPEP | |
| Hydrochloric Acid SCHEMBL27963136 | 0.89 | USP2 (0.72) | USP2ALDH1A1KDM4EPOLBANPEP | |
| SCHEMBL709506 | 0.78 | USP2 (1.00) | USP2ALDH1A1KDM4EPOLBANPEP | |
| SCHEMBL4495691 | 0.76 | USP2 (0.64) | USP2ALDH1A1KDM4EANPEPHSD17B10 | |
| SCHEMBL4493204 | 0.76 | USP2 (0.64) | USP2ALDH1A1KDM4EANPEPHSD17B10 | |
| SCHEMBL4509344 | 0.76 | USP2 (0.64) | USP2ALDH1A1KDM4EANPEPHSD17B10 | |
| SCHEMBL719936 | 0.76 | MEN1 (0.52) | USP2KDM4EHSD17B10L3MBTL1TSHR | |
| SCHEMBL8577369 | 0.75 | HSD17B10 (0.69) | USP2ALDH1A1KDM4EPOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958515-A | Amino-substituted imidazopyridazines | BAYER IP GMBH | 2014-07-30 | — | — | CN | disclosed |