Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488658 | 0.90 | MEN1 (0.68) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL5241239 | 0.90 | MEN1 (0.68) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL488845 | 0.90 | MEN1 (0.68) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL689191 | 0.89 | KDM4E (0.51) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL11218218 | 0.89 | ALOX15 (0.56) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL10321382 | 0.89 | KDM4E (0.51) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL10320703 | 0.89 | KDM4E (0.51) | MEN1KMT2AKDM4EUSP2ATM | |
| Ammonia Solution, Strong SCHEMBL488859 | 0.87 | MEN1 (0.65) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL5241128 | 0.87 | MEN1 (0.73) | MEN1KMT2AKDM4EUSP2ATM | |
| SCHEMBL5243196 | 0.87 | MEN1 (0.73) | MEN1KMT2AKDM4EUSP2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604255-B1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER INC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-8759499-B2 | Lipids for transfection of Eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| EP-2604255-A1 | Novel reagents for transfection of eukaryotic cells | Molecular Transfer, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2015780-B1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER INC (US) | 2012-12-12 | — | — | EP | disclosed |
| US-20120052574-A1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-7915230-B2 | Reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER (US) | 2009-01-22 | — | — | US | disclosed |
| EP-2015780-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | Molecular Transfer, Inc. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007130073-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | FUS, PHAX, PICALM | MEN1 1559/4885KMT2A 4019/4885KDM4E 4645/4885 |
| US-20120052574-A1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | FUS, PHAX, PICALM | MEN1 1559/4885KMT2A 4019/4885KDM4E 4645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.