Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973537 | 0.76 | MAPT (0.69) | ALDH1A1TDP1TSHRMAPTMEN1 | |
| SCHEMBL16414817 | 0.75 | BRD4 (0.59) | BRD4ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4578254 | 0.72 | TDP1 (0.50) | ALDH1A1TDP1TSHRMAPTMEN1 | |
| SCHEMBL21145379 | 0.71 | MAPT (0.50) | ALDH1A1TDP1TSHRMAPTMEN1 | |
| SCHEMBL29465715 | 0.70 | KCNH2 (0.62) | TDP1TSHRMAPTMEN1POLB | |
| SCHEMBL1065088 | 0.70 | KCNH2 (0.62) | TDP1TSHRMAPTMEN1POLB | |
| SCHEMBL1068671 | 0.70 | MAPT (0.48) | ALDH1A1TDP1TSHRMAPTMEN1 | |
| SCHEMBL13737282 | 0.70 | TSHR (0.47) | ALDH1A1TDP1TSHRMAPTMEN1 | |
| SCHEMBL13735401 | 0.69 | MAPT (0.55) | ALDH1A1TDP1TSHRSMN1; SMN2MAPT | |
| SCHEMBL31570099 | 0.68 | MAPT (0.58) | ALDH1A1TDP1TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833671-A | Dihydrothiazolone compound, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2014-06-04 | — | — | CN | disclosed |