Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.67 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 7/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384482 | 0.98 | APP (0.65) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL11959810 | 0.96 | APP (0.62) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL31589824 | 0.89 | APP (0.56) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL5429670 | 0.89 | APP (0.75) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL10045302 | 0.89 | APP (0.56) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL13477886 | 0.89 | APP (0.56) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL27159530 | 0.89 | APP (0.81) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL32677328 | 0.89 | APP (0.81) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL12405207 | 0.89 | APP (0.59) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL14077281 | 0.88 | APP (0.54) | APPHSD17B1HSD17B2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104119311-B | A kind of 2,6-diaryl naphthalene compounds and preparation method thereof | HANGZHOU NORMAL UNIVERSITY (CN) | 2016-02-03 | — | — | CN | claimed |
| CN-104119311-B | A kind of 2,6-diaryl naphthalene compounds and preparation method thereof | HANGZHOU NORMAL UNIVERSITY (CN) | 2016-02-03 | — | — | CN | disclosed |
| CN-104119311-A | 2,6-diaryl naphthalene compound and preparation method thereof | UNIV HANGZHOU NORMAL | 2014-10-29 | — | — | CN | disclosed |