Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364493 | 0.81 | ALDH1A1 (0.31) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL9369268 | 0.75 | — | — | |
| SCHEMBL6695503 | 0.71 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL4955107 | 0.69 | KDM4E (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11525254 | 0.69 | MEN1 (0.40) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL24663899 | 0.68 | DPP4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL21801417 | 0.67 | SMN1; SMN2 (0.40) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL15193817 | 0.65 | SMN1; SMN2 (0.42) | ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL28944497 | 0.65 | CHRM2 (0.38) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL14810348 | 0.65 | CHRM2 (0.45) | CHRM2CHRM1CHRM4CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114549-A | Novel pyrrolidine derivatives | HOFFMANN LA ROCHE | 2014-10-22 | — | — | CN | disclosed |