Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GALR2 | O43603 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661697 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL12489268 | 0.85 | PDGFRB (0.50) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL31071396 | 0.85 | PDGFRB (0.50) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL8322183 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL27793943 | 0.82 | MAPT (0.37) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL28813411 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL27772700 | 0.80 | TSHR (0.46) | ALDH1A1POLBSMN1; SMN2HPGDNPC1 | |
| SCHEMBL31607751 | 0.79 | KDM4E (0.58) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL27137899 | 0.79 | KDM4E (0.58) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL10487718 | 0.78 | POLB (0.57) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605320-B | Synthesis method of 5-nitro-6-methylnicotinic acid ethyl ester | 南京艾康生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-114605320-B | Synthesis method of 5-nitro-6-methylnicotinic acid ethyl ester | 南京艾康生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-114605320-A | Synthesis method of 5-nitro-6-methylnicotinic acid ethyl ester | 南京艾康生物科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114605320-A | Synthesis method of 5-nitro-6-methylnicotinic acid ethyl ester | 南京艾康生物科技有限公司 | 2022-06-10 | — | — | CN | disclosed |