SCHEMBL28814005

SCHEMBL28814005

Cc1ccc(-c2cc(C(=O)NC(C)c3cnc(C)nc3)cc(S(=O)(=O)CC=CC3CCCC3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 12/20 0.43
P2RX2 Q9UBL9 12/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1495841 0.83 P2RX3 (0.47) P2RX3P2RX2
SCHEMBL1495482 0.83 P2RX3 (0.46) P2RX3P2RX2
SCHEMBL1495793 0.83 P2RX3 (0.46) P2RX3P2RX2
SCHEMBL1495427 0.81 P2RX3 (0.46) P2RX3P2RX2
SCHEMBL1495457 0.81 P2RX3 (0.45) P2RX3P2RX2
SCHEMBL27823462 0.80 P2RX3 (0.36) P2RX3P2RX2
SCHEMBL28814009 0.79 P2RX3 (0.44) P2RX3P2RX2
SCHEMBL1495824 0.79 P2RX3 (0.46) P2RX3P2RX2
SCHEMBL1495426 0.79 P2RX3 (0.46) P2RX3P2RX2
SCHEMBL1495653 0.78 P2RX3 (0.46) P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104058999-A Amide Compounds, Compositions And Uses Thereof RENOVIS INC 2014-09-24 CN disclosed
CN-104016907-A Amide compounds, compositions and uses thereof RENOVIS INC 2014-09-03 CN disclosed