SCHEMBL28814528

SCHEMBL28814528

CCC(Br)(c1cccnc1)c1cccnc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.47
KCNA5 P22460 2/20 0.44
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
LMNA P02545 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
KIF11 P52732 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13194995 0.79 CYP19A1 (0.52) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL10191716 0.79 CYP19A1 (0.52) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL26479501 0.78 CYP19A1 (0.49) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL10299579 0.76 KCNA5 (0.50) CYP19A1KCNA5CYP1A2CYP3A4CYP2C9
SCHEMBL18193367 0.76 KCNA5 (0.50) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL10046085 0.76 CYP19A1 (0.49) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL27996644 0.76 CYP19A1 (0.57) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL5720374 0.75 CYP19A1 (0.50) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL5999695 0.75 KCNA5 (0.49) CYP19A1KCNA5CYP1A2CYP3A4LMNA
SCHEMBL27557019 0.75 KCNA5 (0.49) CYP19A1KCNA5CYP1A2CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103992265-A Double tribromo 1,3-bipyridine onium salt dimethylmethane, and preparation method, application method, recovery method and application thereof UNIV XI AN JIAOTONG 2014-08-20 CN claimed
CN-103992265-B Two three bromo 1,3-bis-pyridine alkali propane and preparation method thereof, using method, recovery method and application XI'AN JIAOTONG UNIVERSITY (CN) 2016-02-24 CN disclosed
CN-103992265-A Double tribromo 1,3-bipyridine onium salt dimethylmethane, and preparation method, application method, recovery method and application thereof UNIV XI AN JIAOTONG 2014-08-20 CN disclosed