Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.63 |
| ▸ | CES1 | P23141 | 7/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.50 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184435 | 0.89 | TSHR (0.70) | CES2CES1TSHRSRD5A2NPC1 | |
| SCHEMBL333237 | 0.83 | SRD5A2 (0.78) | TSHRSRD5A2NPC1RAB9AHSD11B1 | |
| SCHEMBL906513 | 0.83 | TSHR (0.68) | TSHRSRD5A2NPC1RAB9A | |
| SCHEMBL728125 | 0.81 | TSHR (0.50) | CES2CES1TSHRSRD5A2NPC1 | |
| SCHEMBL4035546 | 0.80 | MEN1 (0.60) | CES2CES1TSHRSRD5A2NPC1 | |
| Benzil SCHEMBL4957522 | 0.79 | CES2 (1.00) | CES2CES1TSHRSRD5A2RAB9A | |
| SCHEMBL1195835 | 0.79 | CES2 (1.00) | CES2CES1TSHRSRD5A2RAB9A | |
| SCHEMBL5650766 | 0.79 | TSHR (0.57) | TSHRSRD5A2NPC1RAB9AHSD11B1 | |
| SCHEMBL8352471 | 0.78 | TSHR (1.00) | TSHRSRD5A2NPC1RAB9AALOX15 | |
| SCHEMBL912515 | 0.78 | CES2 (1.00) | CES2CES1TSHRSRD5A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102906215-B | Photochromic material | MITSUBISHI GAS CHEMICAL CO | 2014-11-05 | — | — | CN | disclosed |